Research presented in Frontiers of Medicine delves into the regulatory role of the long non-coding RNA (lncRNA) ZNF593-AS in cardiac hypertrophy and myocardial remodeling, processes that are pivotal ...

UC Santa Cruz researchers have discovered a peptide in human RNA that regulates inflammation and may provide a new path for treating diseases such as arthritis and lupus. The team used a screening ...

An Immune-metabolic signature (IMMETCOLS) identifies three clusters in mCRC with different immune-phenotype distribution and potential clinical implications. Deep neural networks and association with ...

Sometimes highly impactful serendipitous discoveries are made when performing genetic loss-of-function studies that were initially focused on putative tumor suppressors or other hypotheses.

New study reveals how cytoplasmic and nuclear functions of USP30-AS1 converge to promote tumor growth Breast cancer progression is increasingly ...

A newly revealed role of lncRNAs in the deadly malaria parasite, Plasmodium falciparum, has opened new avenues for targeted therapeutic strategies. Malaria continues to be one of the most critical ...

Patients with overproduction of protein from the chromodomain helicase DNA binding (CHD2) gene can develop a very rare and severe neurodevelopmental disorder with profound implications for their ...

The vast non-coding portion of the human genome has had many names, including ‘junk’ and ‘dark matter.’ But research, including the international ENCODE project, has shown that these regions are ...