Major histocompatibility complex class II (MHC-II) molecules play a critical, yet historically overlooked, role in tumor immunity. This review synthesizes emerging mechanistic evidence showing that ...

The colorful dots at the center are cytotoxic granules used to destroy infected or cancerous cells. Credit: F. Lemaitre @ ...

Cancer immunotherapy has transformed cancer treatment, yet many patients experience limited or short-lived responses due to immune evasion, tumor heterogeneity, and immune-related adverse events.

The major histocompatibility complex (MHC) region plays a crucial role in immune function; therefore, any genetic or epigenetic polymorphisms within the MHC locus may result in various diseases, as ...

MIT engineers have developed a new way to amplify the T-cell response to mRNA vaccines—an advance that could lead to much more powerful cancer vaccines and stronger protection against infectious ...

Treating the brain cancer glioblastoma (GBM) demands more than conventional strategies due to a mix of factors including the cancer’s genetic complexity, invasive growth, and immune resistance. A new ...

Enhanced Signal-to-Noise Ratio as a Primary Advantage of MBLI Tetramers Concerning Biological Interactions with Dextran. In this blog, we will discuss the increasing evidence in the literature and ...

CAR T-cell therapy, which transforms patients’ own immune cells into cancer-fighting warriors, has revolutionized how physicians treat cancer, especially blood cancers. “These patients can be cured ...

Researchers in Japan have discovered a new type of antibody, called an immune-induced TCR-like antibody (iTab), that can selectively suppress harmful T cells without dampening the entire immune system ...