In the early and mid-1980s, scientists used phages to express recombinant proteins. The protein was retained inside the virions, so screening required growing viral plaques, creating a stamp of these ...

Reviewed by Michael Greenwood, M.Sc. In phage-display, a gene encoding the surface protein of a bacteriophage is replaced with a gene encoding a novel protein. The technique can be used in drug ...

When a person receives a cancer diagnosis, treatment can often include chemotherapy. This method of treating cancer also can affect healthy cells. But what if there was a drug on the market that, ...

Aga2-fusion protein binding to yeast cell by Aga1. Image provided by Invitrogen. Phage display systems, reviewed in a recent issue of The Scientist, 1 have proven enormously useful for the detection ...

Mapping the individual amino acids where antibodies bind (epitopes) to target viral proteins (antigens) is crucial to predicting how target proteins may evolve to escape antibody binding, improve ...

mRNA display is a technique that can identify proteins which bind to specific regions in DNA. This method has several advantages over other methods, such as yeast-to-hybrid, immunoprecipitation, phage ...