Lead antibody MB0109 targets C1q and uniquely inhibits both classical complement cascade and C1q-mediated macrophage/microglial activation — two ...

“Most people probably think that inflammation in the brain is something bad and that you should inhibit the inflammatory system in case of illness. But inflammation doesn’t just have to be negative,” ...

Researchers rely on TSPO PET imaging to evaluate neuroinflammation in living people. But what does this signal actually measure? In a May 11 preprint on bioRxiv, researchers led by David Owen at ...

Scientists show that lecanemab clears amyloid plaques by engaging microglia through its Fc fragment, defining the cellular program behind its therapeutic effect ...

Announcing a new article publication for BIO Integration journal. Alzheimer's disease (AD) is a neurodegenerative disorder ...

Foralumab reduced microglial activity in people with nonactive SPMS, and this was linked to reductions in proinflammatory ...

Researchers uncover how manual acupuncture targets spinal inflammation to relieve rheumatoid arthritis pain. Read more!

Tiziana Life Sciences Announces New Biomarker Data Showing Nasal Foralumab Downregulates CSF Inflammation, Upregulates Neuroprotective Pathways, and Correlates with Reduced Microglial Activation on ...

Microglia, immune cells of the brain, have recently gained recognition for their neuroprotective function; now meet the molecule that makes it happen. Researchers at University of Virginia Health ...

As neuronal supporters and immune surveyors, astrocytes and microglia are no mere bystanders to the neuronal mayhem that unfolds in Alzheimer’s disease. At the AD/PD meeting, held March 5-9 in Lisbon, ...