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Colorectal cancer has a backup plan, and it begins when mature gut cells regain stem-like traits
In a recent study, Stevens researchers have shown how colorectal cancers can evolve from mature intestinal cells that revert ...
Gut stem cells can detect invading bacteria and transform into bacteria-killing cells, revealing an unexpected immune defense ...
Researchers have developed a human intestinal cell model that closely mimics the structure and function of the human gut, enabling more precise prediction of drug-induced gastrointestinal toxicity ...
Human organoids are 3D cell cultures derived from adult stem cells and maintain the variable distribution of epithelial cells seen in primary tissue. They can recapitulate the mechanisms of epithelial ...
A miniaturized, biomimetic model of the human intestine has successfully reproduced long-term enterovirus A71 (EV-A71) ...
Researchers have solved a cellular mystery that may lead to better therapies for colorectal and other types of cancer. A professor of pediatrics-developmental biology and an assistant professor of ...
A research team led by scientists from the State University of Campinas (UNICAMP) in São Paulo, Brazil, has made significant progress in understanding the relationship between gut microbiota and ...
A new study reported in Nature has determined that the amino acid cysteine could promote regeneration among cells in the small intestine. The work showed that cysteine can activate an immune signaling ...
When inflammation damages the intestinal lining, differentiated enterocytes and crypt base columnar stem cells (CBCs) revert to a regenerative, fetal-like state and form revival stem cells (revSCs).
Researchers found that a small population of immune cells in the mouse intestine prevents allergic responses to food, suggesting that targeting such cells therapeutically could potentially lead to a ...
Eating is one of life’s few constants: If you’re not eating right now, you’ll certainly be eating something within a few hours. But when and how often we should eat is still not fully understood.
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