Pasca Lab specializes in growing three-dimensional organoid models from reprogrammed stem cells, which capture molecular changes during fetal brain-like development. Because the human brain cannot be ...

Rapidly testing hundreds of thousands of DNA sequences, scientists identified specific genetic variations contributing to blood pressure, cholesterol, and blood sugar.

Scientists have identified how specific genetic changes function in cells to influence disease risk and other human health traits. By probing regions of DNA previously linked to disease, the work has ...

A major medical milestone took place in May 2025, when doctors at the Children’s Hospital of Philadelphia used CRISPR-based gene editing to treat a child with a rare genetic disorder. Unlike earlier ...

Genes may play a bigger role in living a longer life, while lifestyle and luck still shape the outcome, according to a new ...

Thanks to increasingly efficient and affordable gene sequencing technologies, we can now chart our genetic blueprint in unprecedented detail. But what does each gene do? Of the roughly 20,000 genes ...

A version of this Priestley Medal address will be presented at the American Chemical Society Spring 2026 meeting ...

There are over 100 types of human papillomavirus (HPV), and some can lead to different types of cancer, including cancer that affects the nose and throat. These are known as HPV-associated ...