How exactly do amyloid plaques affect surrounding brain tissue, and does this change over time? Scientists led by Jörg Hanrieder at the University of Gothenburg, Sweden, tackled this question by using ...
Scientists broadly agree that both apolipoprotein E and microglia are necessary ingredients for amyloidosis. In mice devoid of ApoE, or of their microglia, scant plaques form. Now, a sweeping study ...
He added that this work shows plaques to be very dynamic -- that is, they can form quickly and be removed quickly. Researchers have previously thought that all plaques are slow to form and long-lived.
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