(A) Representative histological images of liver tissues from patients with steatosis, MASH, and liver fibrosis by hematoxylin-eosin or Masson's trichrome staining. The arrows mark the ballooned ...

Metabolic dysfunction-associated steatotic liver disease (MASLD) has a prevalence of about 25% in the adult population, with steatosis present in >5% of hepatocytes, hepatocyte ballooning and fibrosis ...

AML12 cells were transfected with Scram (control) or miR-34a mimics for 48 h and subjected to the following analysis (A–D). (A) Hematoxylin-eosin staining and microscope imaging of the transfected ...

Understanding how these functions impact a given compound is essential for effective preclinical drug development. Hepatocytes comprise approximately 80 % of the liver’s volume but only represent ...