Cocaine addiction may persist because the drug rewires brain circuits through a protein called DeltaFosB. This buildup ...

Researchers have used mouse models to study how cocaine addiction alters the brain, illuminating why relapse is common as well as possible treatment options.

Remarkable scientific progress over the past five decades has helped us develop knowledge of how drugs of abuse induce pleasure, reinforce use, and lead to the compulsive self-administration we call ...

What if a single choice could hijack your brain’s wiring, rewriting your behavior, judgment, and even your ability to survive? The human brain is an essential organ in the body, responsible for ...

A nonprofit called RIZE Prevention aims to stop substance abuse in teens before it begins. The program mentors sixth through eighth graders, teaching coping skills and building relationships. RIZE ...