A new research perspective was published in Volume 13 of Oncoscience on June 3, 2026, titled "The dual axis of tumorigenesis: ...

The central image depicts currently used strategies for clinical targeting of TGF-β. Below are methods applicable from preclinical screening to clinical practice, including using humanized mouse ...

Cancer drug resistance is the devastating reason that treatments fail and cancers metastasize, spreading to distant sites seeding new resistant tumors elsewhere in the body. Combating the problem has ...

Laboratory studies suggest cinnamon’s bioactive compounds can alter key cancer-related signaling pathways, but researchers caution that human trials are essential before any preventive or therapeutic ...

Scientists from the Perelman School of Medicine at the University of Pennsylvania and their colleagues have identified a cell surface receptor protein called TIE2 as a critical component of two key ...

Microscopic images of cranial blood vessels show the growth of mulberry-shaped CCMs over a 21 day period in control mice (top two rows). This growth is prevented by treatment with the TIE2 inhibitor ...