Since the 1 920s, when researchers began to study chromosomes, the analysis of human chromosomes has presented a particularly tough technological challenge, simply because there are so many of them.

The Cytogenetics Laboratory performs chromosome analysis, fluorescence in situ hybridization (FISH), and array comparative genomic hybridization (array CGH) on cells prepared from a wide variety of ...

Pt. A. Gene cloning -- cDNA cloning method using stable expression in mammalian cells / Toru Miki and Stuart A. Aaronson -- Normalization and selection with short-fragment cDNAs / Satish Parimoo, ...

Cost-effective oligo system design schematic. Each synthetic oligo consists of two oligos (oligo-A and oligo-B), one forward primer (Primer-A), and two reverse primers (Primer-B and Primer-C). (A) ...

Karyotype analysis includes complete chromosome analysis of at least twenty metaphases with at least two cut karyotypes. The presence or absence of an acquired clonal chromosomal abnormality may aid ...

In female mammals, one of the two X chromosomes is usually inactive and forms the so-called Barr body. The image shows a cell nucleus with the Barr body marked in green. Unlike men, who carry one X ...

New @hopkinskimmel research finds extra copies of chromosome 1q may drive the earliest stages of pancreatic cancer. › ...

Researchers at the Francis Crick Institute, working with the University of Oxford, University of York, and Oxford Archaeology, have developed a new technique to measure the number of chromosomes in ...

By late life, a surprising share of men have blood cells that no longer carry the Y chromosome at all, according to large genetic studies in cohorts such as the UK Biobank. That quiet genetic drift ...

By late middle age, as many as four in ten men have quietly lost the Y chromosome in some blood cells. Scientists are now ...